Osteoporosis--a risk factor for cardiovascular diseases: a follow-up study.
نویسندگان
چکیده
INTRODUCTION Cardiovascular (CV) diseases and bone fractures due to osteoporosis are the leading causes of death in the elderly. OBJECTIVE The aim of this study was to demonstrate a correlation between the overall risk for CV events, and low bone density in postmenopausal women, and its impact on the incidence of serious CV events. METHODS Our prospective study involved 300 postmenopausal women. All the examinees were divided into three groups based on their measured bone density: Group I--84 examinees with osteoporosis; Group II--115 examinees with osteopenia; and Group III--101 examinees with normal bone density. In all examinees the overall ten-year risk for a fatal CV event was calculated using the SCORE system tables. RESULTS After a 36-month follow-up, CV events occurred in 19 (6.3%) examinees. Significant differences in the incidence of CV events were demonstrated between the patients with osteoporosis, osteopenia, and normal bone density (χ2 = 28.7; p < 0.001), as well as between those with a high and low CV risk (χ2 = 22.6; p < 0.001). Multivariate logistic regression analysis showed that smoking (OR: 2.23; 95% CI: 1.02 to 6.19; p = 0.035), and increase of overall CV score (OR: 1.36; 95% CI: 1.17 to 1.58; p < 0.001) are associated with increased CV event risk, while the increase of T score value is associated with decreased risk of CV event (OR: 0.42; 95% CI: 0.25 to 0.73; p = 0.002). CONCLUSION Measurement of bone density with a standard assessment of the total CV risk could be useful for selecting women who need intensive prevention and treatment of atherosclerosis.
منابع مشابه
Adherence to Iran’s Package of Essential Noncommunicable Diseases (IraPEN) Program for Regular Follow-up to Reduce the Risk of Cardiovascular Disease in Healthcare Centers
Participantschr(chr(chr(chr('39')39chr('39'))39chr(chr('39')39chr('39')))39chr(chr(chr('39')39chr('39'))39chr(chr('39')39chr('39')))) adherence to the IraPEN program for regular follow-up to reduce the risk of cardiovascular disease in healthcare centers Introduction: In Iran, as in most West Asian countries, cardiovascular disease is the leading cause of death and accounts for 46% of deaths. ...
متن کاملThe Effect of Osteoporosis Prevention Empowerment Program on the Self-Efficacy of Iranian Older Adults
Background: Osteoporosis is characterized by low bone mass and loss of the quality of bone microarchitecture. These changes increase the probability of bone fracture. This study aimed to determine the effect of an empowerment program based on the Health Belief Model (HBM) on the self-efficacy of older adults to prevent osteoporosis. Methods: It was a randomized controlled trial with pre-test, ...
متن کاملCardiovascular risk factors in patients with psoriasis: A casecontrol study
Recent studies suggest that psoriasis may be an independent risk factor for the development of cardiovascular diseases. Myocardial infarction, pulmonary embolism, diabetes mellitus,hypertension, and dyslipidemia have been reported in patients with psoriasis Certain risk factors for cardiovascular diseases may be more prevalent among patients with psoriasis 3,4. The aim of this study was to defi...
متن کاملSocioeconomic Status and Osteoporosis Risk: A Case-control Study in Outpatient Women in Yazd
Introduction: Osteoporosis is a skeletal disorder that reduces bone strength and ultimately increases the risk of fractures. The socioeconomic status is one of the important factors affecting health, and it is confirmed as a predictor of various diseases and deaths. This study aimed to determine the relationship between osteoporosis and socioeconomic status. Methods: This study was a case-cont...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Srpski arhiv za celokupno lekarstvo
دوره 143 1-2 شماره
صفحات -
تاریخ انتشار 2015